BDBM50085972 CHEMBL7143::[2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimethyl-amine::[2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimethyl-amine (C2H2O)::[2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimethyl-ammonium

SMILES COc1ccc2[nH]c(C)c(CCN(C)C)c2c1

InChI Key InChIKey=ACEHBQPPDDGCGZ-UHFFFAOYSA-N

Data  15 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50085972   

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972(CHEMBL7143 | [2-(5-Methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataKi:  60nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972(CHEMBL7143 | [2-(5-Methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataKi:  60nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972(CHEMBL7143 | [2-(5-Methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataKi:  80nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptor expressed in HEK 293 human embryonic kidney cells, [3H]-lysergic acid diethylamide as radio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972(CHEMBL7143 | [2-(5-Methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataKi:  89nMAssay Description:Binding affinity as displacement of [3H]-5-HT binding to 5-hydroxytryptamine 6 receptor in HeLa cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972(CHEMBL7143 | [2-(5-Methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataKi:  145nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972(CHEMBL7143 | [2-(5-Methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataKi:  200nMAssay Description:Compound was evaluated for its binding affinity towards human human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972(CHEMBL7143 | [2-(5-Methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataKi:  250nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rat)
State University of Groningen

Curated by ChEMBL
LigandPNGBDBM50085972(CHEMBL7143 | [2-(5-Methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataKi:  1.12E+3nMAssay Description:Binding affinity at rat 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972(CHEMBL7143 | [2-(5-Methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataKi:  1.26E+3nMAssay Description:Binding affinity of compound towards rodent 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1E(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972(CHEMBL7143 | [2-(5-Methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataKi:  1.80E+3nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 1E receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972(CHEMBL7143 | [2-(5-Methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataKi:  4.02E+3nMAssay Description:Compound was evaluated for its binding affinity towards rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972(CHEMBL7143 | [2-(5-Methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataKi:  6.38E+3nMAssay Description:Compound was evaluated for its binding affinity towards human NET (norepinephrine) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972(CHEMBL7143 | [2-(5-Methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for its binding affinity towards human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972(CHEMBL7143 | [2-(5-Methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for its binding affinity towards rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085972(CHEMBL7143 | [2-(5-Methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataKi:  1.05E+4nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 5A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed