BDBM50092660 4-Amino-benzamidine::4-aminobenzamidine::CHEMBL124632::CHEMBL545184::US11584714, Compound 47a::p-aminobenzamidine

SMILES NC(=N)c1ccc(N)cc1

InChI Key InChIKey=WPANETAWYGDRLL-UHFFFAOYSA-N

Data  4 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50092660   

TargetSerine protease 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50092660(4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...)
Affinity DataKi:  8.90E+3nMAssay Description:Inhibition of human recombinant trypsin 1 using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin-3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50092660(4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...)
Affinity DataKi:  1.31E+4nMAssay Description:Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandPNGBDBM50092660(4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...)
Affinity DataKi:  6.25E+4nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetProthrombin(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50092660(4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...)
Affinity DataKi:  9.50E+4nMAssay Description:Inhibition of human thrombin using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50092660(4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...)
Affinity DataKd:  7.80E+4nMAssay Description:Binding affinity to human alpha thrombin by Biocore A100 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092660(4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory activity against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed