BDBM50094684 2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine::CHEMBL146658

SMILES Nc1nc2nn(CCc3cccc4ccccc34)cc2c2nc(nn12)-c1ccco1

InChI Key InChIKey=KVPYVHAQCCBFJP-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50094684   

TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094684(2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyrazo...)
Affinity DataKi:  348nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells; range 267-453More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094684(2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyrazo...)
Affinity DataKi:  896nMAssay Description:Displacement of [3H]-SCH- 58261 from human adenosine A2A receptor expressed in CHO cells; range 730-1100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094684(2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyrazo...)
Affinity DataKi:  3.42E+3nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094684(2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyrazo...)
Affinity DataKi:  3.42E+3nMAssay Description:Displacement of [3H]-MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells; range 3228-3614More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094684(2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyrazo...)
Affinity DataKi:  4.29E+3nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A2b receptor expressed in CHO cells; range 3828-4817More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094684(2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyrazo...)
Affinity DataKi:  3.39E+6nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed