BDBM50095965 CHEMBL3593764

SMILES CS(=O)(=O)N1CCC(CC1)Nc1c(cnc2[nH]ccc12)C(N)=O

InChI Key InChIKey=BIXYYZIIJIXVFW-AVUCVXPCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095965   

TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50095965(CHEMBL3593764)
Affinity DataIC50:  150nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50095965(CHEMBL3593764)
Affinity DataIC50:  190nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed