BDBM50096230 CHEMBL3594178

SMILES CCN(C[C@H]1CC[C@H](N)CC1)c1nccc(Nc2cc([nH]n2)[C@H]2CCN(C)C2=O)n1

InChI Key InChIKey=ONHTZJLXGIZPCI-OEMZLSOOSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50096230   

TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50096230(CHEMBL3594178)
Affinity DataKi:  49nMAssay Description:Inhibition of PAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase PAK 4(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50096230(CHEMBL3594178)
Affinity DataKi:  621nMAssay Description:Inhibition of PAK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAurora kinase A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50096230(CHEMBL3594178)
Affinity DataKi: >5.40E+3nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50096230(CHEMBL3594178)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as inhibition of MEK phosphorylation at S298More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed