BDBM50099692 CHEMBL51314::N-(9,10-Dioxo-9,10-dihydro-phenanthren-2-yl)-2,2-dimethyl-propionamide::N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-dimethyl-propionamide::N-(9,10-dioxo-9,10-dihydrophenanthren-2-yl)-2,2-dimethylpropionamide

SMILES CC(C)(C)C(=O)Nc1ccc-2c(c1)C(=O)C(=O)c1ccccc-21

InChI Key InChIKey=VZQDDSYKVYARDW-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50099692   

TargetReceptor-type tyrosine-protein phosphatase C(Human)
United States Army Medical Research Institute of Infectious Diseases

LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  400nMAssay Description:Protein phosphatases were purchased from Upstate Biotechnology (Lake Placid, NY).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory concentration against FAP-1 pNPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  400nMAssay Description:Inhibitory concentration against Cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor-type tyrosine-protein phosphatase C(Human)
United States Army Medical Research Institute of Infectious Diseases

LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibitory concentration against CD45 protein-tyrosine phosphatase using lck-10 mer as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against FAP-1 using lck-10 mer as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of protein tyrosine phosphatase N13 (unknown origin) phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor-type tyrosine-protein phosphatase C(Human)
United States Army Medical Research Institute of Infectious Diseases

LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProcathepsin L(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  500nMAssay Description:Inhibitory concentration against Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lck(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of Lck (unknown origin) phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of protein tyrosine phosphatase N1 (unknown origin) phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against PTP1B using lck as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed