BDBM50101416 CHEMBL307488::[(R)-2-(3H-Indol-3-yl)-1-methyl-1-((S)-1-phenyl-ethylcarbamoyl)-ethyl]-carbamic acid benzofuran-2-ylmethyl ester::[2-(1H-Indol-3-yl)-1-methyl-1-(1-phenyl-ethylcarbamoyl)-ethyl]-carbamic acid benzofuran-2-ylmethyl ester

SMILES C[C@H](NC(=O)[C@@](C)(Cc1c[nH]c2ccccc12)NC(=O)OCc1cc2ccccc2o1)c1ccccc1

InChI Key InChIKey=IVIQHHCTWSXXCT-WENCNXQZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101416   

TargetSubstance-P receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50101416(CHEMBL307488 | [(R)-2-(3H-Indol-3-yl)-1-methyl-1-(...)
Affinity DataIC50:  1.05nMAssay Description:Inhibition of specific binding at tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50101416(CHEMBL307488 | [(R)-2-(3H-Indol-3-yl)-1-methyl-1-(...)
Affinity DataIC50:  0.550nMAssay Description:Binding affinity towards tachykinin receptor 1 in human IM9 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50101416(CHEMBL307488 | [(R)-2-(3H-Indol-3-yl)-1-methyl-1-(...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50101416(CHEMBL307488 | [(R)-2-(3H-Indol-3-yl)-1-methyl-1-(...)
Affinity DataIC50:  5.90nMAssay Description:In vitro affinity for specific binding at Gerbil tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed