BDBM50105000 CHEMBL175616::sodium salt of 4-tert-Butyl-N-[6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
SMILES COc1ccccc1Oc1c([N-]S(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1
InChI Key InChIKey=UJGUMHQLVYROSG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50105000
Affinity DataKi: 81nMAssay Description:Ability to inhibit [125I]ET1 binding to human cloned endothelin A receptor expressed on CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Ability to inhibit [125I]-ET-1 binding to human cloned ETB receptors expressed on CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Ability to inhibit specific binding of [125I]- -ET-1 to human GH cells which express endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:In vitro for specific binding of [125I]-ET-1 to A10 cell expressed in endothelin A receptorMore data for this Ligand-Target Pair