BDBM50106431 1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoline-3-carboxylic acid::CHEMBL292700

SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(O)c(O)c1

InChI Key InChIKey=ZCMFEWUYBFMLIN-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50106431   

TargetInsulin-like growth factor-binding protein 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  1nMAssay Description:The compound was tested for binding affinity against Insulin-like growth factor binding protein 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInsulin-like growth factor-binding protein 2(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  2.10nMAssay Description:The compound was tested for binding affinity against insulin-like growth factor binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInsulin-like growth factor-binding protein 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  5.10nMAssay Description:The compound was tested for binding affinity against insulin-like growth factor binding protein 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInsulin-like growth factor-binding protein 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  5.20nMAssay Description:The compound was tested for binding affinity against Insulin-like growth factor binding protein 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInsulin-like growth factor-binding protein 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  5.60nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInsulin-like growth factor-binding protein 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  5.60nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInsulin-like growth factor-binding protein 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  5.60nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInsulin-like growth factor-binding protein 6(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  24nMAssay Description:The compound was tested for binding affinity against Insulin-like growth factor binding protein 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed