BDBM50109063 (3-Azepan-1-yl-propyl)-benzo[1,3]dioxol-5-ylmethyl-(3-p-tolyl-isoxazol-5-yl)-amine::CHEMBL111258

SMILES Cc1ccc(cc1)-c1cc(on1)N(CCCN1CCCCCC1)Cc1ccc2OCOc2c1

InChI Key InChIKey=CDYMXRUWHVBUKR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50109063   

TargetProteinase-activated receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109063((3-Azepan-1-yl-propyl)-benzo[1,3]dioxol-5-ylmethyl...)
Affinity DataIC50:  140nMAssay Description:Antagonistic activity against thrombin receptor, inhibition of secreted radiolabeled [3H]-5-HT from washed human platelets stimulated by 3 microM thr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109063((3-Azepan-1-yl-propyl)-benzo[1,3]dioxol-5-ylmethyl...)
Affinity DataIC50:  290nMAssay Description:Inhibition of secretion of radiolabeled serotonin from washed human platelets stimulated by 1 nM thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109063((3-Azepan-1-yl-propyl)-benzo[1,3]dioxol-5-ylmethyl...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of secretion of radiolabeled serotonin from washed human platelets stimulated by 1 nM thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed