BDBM50114666 5-(4-chlorophenyl)-2-furaldehyde thiosemicarbazone::CHEMBL327577

SMILES NC(=S)NN=Cc1ccc(o1)-c1ccc(Cl)cc1

InChI Key InChIKey=OYEQJQNRMFKNDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50114666   

TargetCruzipain(Trypanosoma cruzi)
Federal University of Minas Gerais

Curated by ChEMBL
LigandPNGBDBM50114666(5-(4-chlorophenyl)-2-furaldehyde thiosemicarbazone...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
Federal University of Minas Gerais

Curated by ChEMBL
LigandPNGBDBM50114666(5-(4-chlorophenyl)-2-furaldehyde thiosemicarbazone...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against Trypanosoma cruzi cathepsin L-like protease (cruzain) was determined using purified recombinant proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed