BDBM50118478 CHEMBL3613749

SMILES Cc1ncc(Cl)cc1NCc1ccc(s1)C(=O)N[C@@H](CC1CCCC1)C(=O)NC1CC1

InChI Key InChIKey=IVDUVEGCMXCMSO-FQEVSTJZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118478   

TargetProtein phosphatase 1D(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50118478(CHEMBL3613749)
Affinity DataIC50:  86nMAssay Description:Inhibition of His-tagged PPM1D (1 to 420 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells using Ac-VEPPLS(P)QETFSDLW-N...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1D(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50118478(CHEMBL3613749)
Affinity DataIC50:  6nMAssay Description:Allosteric inhibition of human Wip1 (2 to 420 residues) expressed in baculovirus infected sf9 cells using FDP as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1D(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50118478(CHEMBL3613749)
Affinity DataIC50:  6nMAssay Description:Inhibition of human Wip1 (2 to 420 residues) expressed in baculovirus-infected insect SF9 cells assessed as fluorescein diphosphate hydrolysis after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1D(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50118478(CHEMBL3613749)
Affinity DataIC50:  6nMAssay Description:Inhibition of human Wip1 (2 to 420 residues) expressed in baculovirus-infected insect SF9 cells assessed as fluorescein diphosphate hydrolysis after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed