BDBM50118976 1-(2-Methoxy-acetyl)-4-(4-methoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL97898

SMILES COCC(=O)N1CC(N(Cc2ccccc12)S(=O)(=O)c1ccc(OC)cc1)C(=O)NO

InChI Key InChIKey=PLYLMXDSDZFWLJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118976   

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118976(1-(2-Methoxy-acetyl)-4-(4-methoxy-benzenesulfonyl)...)
Affinity DataIC50:  2nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118976(1-(2-Methoxy-acetyl)-4-(4-methoxy-benzenesulfonyl)...)
Affinity DataIC50:  2nMAssay Description:Concentration of the compound required in vitro to inhibit Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50118976(1-(2-Methoxy-acetyl)-4-(4-methoxy-benzenesulfonyl)...)
Affinity DataIC50:  95nMAssay Description:Concentration required in vitro to inhibit TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118976(1-(2-Methoxy-acetyl)-4-(4-methoxy-benzenesulfonyl)...)
Affinity DataIC50:  34nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed