BDBM50120430 CHEMBL3617964

SMILES Cc1c(cc(C(=O)NCc2ccc(cn2)S(C)(=O)=O)c(=O)n1-c1cccc(c1)C(F)(F)F)-c1ccnn1C

InChI Key InChIKey=QNQZWEGMKJBHEM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120430   

TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120430(CHEMBL3617964)
Affinity DataKi:  12nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val 7-amido-4-methylcoumarin as substrate preincubated for 15 mins followed by subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120430(CHEMBL3617964)
Affinity DataIC50:  12nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed