BDBM50124150 CHEMBL3622830

SMILES NCCn1c(nc2cc(ccc12)C(N)=O)-c1ccc(cc1)C#N

InChI Key InChIKey=FTNJYSPZRLVCRR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50124150   

TargetTyrosine-protein kinase JAK1(Human)
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124150(CHEMBL3622830)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of JAK1 (unknown origin) using 87 uM of ATP and Tyr6 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124150(CHEMBL3622830)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Tyk2 (unknown origin) using 25 uM of ATP and Tyr3 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Human)
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124150(CHEMBL3622830)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of JAK3 (unknown origin) using 16 uM of ATP and Tyr6 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Human)
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124150(CHEMBL3622830)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of JAK2 (unknown origin) using 35 uM of ATP and Tyr6 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed