BDBM50136702 (+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-2,3-diphenylpropan-1-one::1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-2,3-diphenyl-propan-1-one::CHEMBL140260

SMILES COc1cc2CCN(Cc2cc1OC)C(=O)C(Cc1ccccc1)c1ccccc1

InChI Key InChIKey=DRSDLTFJRNRLDX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50136702   

TargetOrexin/Hypocretin receptor type 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136702((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136702((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50:  395nMAssay Description:Antagonist activity at human OX2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136702((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human OX1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136702((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50:  395nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed