BDBM50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2
SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChI Key InChIKey=XIJHWXXXIMEHKW-LJWNLINESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 125 hits for monomerid = 50139013
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 0.00950nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain after 45 minsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 0.490nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 0.690nMAssay Description:Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligandMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 0.690nMAssay Description:Displacement of [3H]DAMGO from Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity to mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]endomorphin-2 from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 1.33nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 1.33nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain P2 synaptosomeMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 1.35nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 2.06nMAssay Description:Binding affinity towards mu receptor in rat brain using [3H]DAMGOMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]DAMGO from rat cortex mu opioid receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]DAMGO from human recombinant MOR expressed in CHO cell membranes incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Inhibition of [3H]-naloxone binding to rat brain homogenate Opioid receptor muMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-endomorphin-2 from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 8.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 8.23nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 8.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 8.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 8.70nMAssay Description:Displacement of [3H]SP1-7 from NK1 receptor in Sprague-Dawley rat spinal cord membraneMore data for this Ligand-Target Pair
Affinity DataKi: 8.70nMAssay Description:Displacement of [3H]SP1-7 from NK1 receptor in Sprague-Dawley rat spinal cord membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Inhibition of DAMGO (Tyr-[D-Ala]-Gly-[NMe-Phe]-Gly-ol) binding to rat brain mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 9.53nMAssay Description:Displacement of [3H]-DAMGO from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 9.56nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 9.60nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 10.6nMAssay Description:Displacement of [3H]-Dynorphin A from Opioid receptor kappa 1 of rat brain membranes (DAMGO/DADLE quenching of mu/delta receptor binding)More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of The Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-DAMGO from Wistar rat mu opioid receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: >500nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: >500nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in calf frontal cortex after 1 hr by gamma counterMore data for this Ligand-Target Pair
Affinity DataKi: 1.14E+3nMAssay Description:Displacement of [3H]U-69593 from human recombinant KOR expressed in CHO cell membranes incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Inhibition of [3H]-naloxone binding to rat brain homogenate Opioid receptor deltaMore data for this Ligand-Target Pair
Affinity DataKi: 2.65E+3nMAssay Description:Displacement of [3H]Ile5,6-deltorphin II from opioid receptor delta 1 of rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.71E+3nMAssay Description:Displacement of [3H]U69,593 from guinea pig cortex/cerebella kappa opioid receptor after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.39E+3nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor (unknown origin) expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.94E+3nMAssay Description:Binding affinity towards delta receptor in rat brain using [3H]DSLETMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Mouse)
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Affinity DataKi: >4.00E+3nMAssay Description:Displacement of [3H]U69,593 from kappa opioid receptor in Hartley guinea pig cerebellum P2 synaptosome membraneMore data for this Ligand-Target Pair
Affinity DataKi: 5.24E+3nMAssay Description:Binding affinity to KOP (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 5.65E+3nMAssay Description:Displacement of [3H]Ile5,6deltorphin-2 from delta opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 6.08E+3nMAssay Description:Displacement of [3H]deltorphin 2 from delta opioid receptor in rat brain P2 synaptosomeMore data for this Ligand-Target Pair
Affinity DataKi: 6.09E+3nMAssay Description:Displacement of [3H]deltorphin 2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
Affinity DataKi: 6.09E+3nMAssay Description:Binding affinity to delta opioid receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 6.42E+3nMAssay Description:Displacement of [3H]DPDPE from Myc-tagged delta opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair