BDBM50148049 (1E)-1-(1,1'-biphenyl-4-yl)ethan-1-one thiosemicarbazone::CHEMBL323975

SMILES CC(=NNC(N)=S)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=XDGIFUBPAVQFCJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148049   

TargetFalcipain 2(Plasmodium falciparum)
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148049((1E)-1-(1,1'-biphenyl-4-yl)ethan-1-one thiosemicar...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of falcipain2 from Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50148049((1E)-1-(1,1'-biphenyl-4-yl)ethan-1-one thiosemicar...)
Affinity DataIC50:  384nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity assessed as decrease in dopachrome formation using L-DOPA as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148049((1E)-1-(1,1'-biphenyl-4-yl)ethan-1-one thiosemicar...)
Affinity DataIC50:  90nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148049((1E)-1-(1,1'-biphenyl-4-yl)ethan-1-one thiosemicar...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed