BDBM50171910 CHEMBL3806110::US10106508, Compound I-30
SMILES COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2c2OCCOc12
InChI Key InChIKey=GSVZKVUECPSJDL-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50171910
Affinity DataIC50: 11nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:The sample compounds were dissolved in DMSO and diluted it to 500 μM concentration with DMSO and transferred to a dose plate. The compounds were...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:The sample compounds were dissolved in DMSO and diluted it to 500 μM concentration with DMSO and transferred to a dose plate. The compounds were...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair