BDBM50173290 4-[5-(2-Fluoro-ethyl)-3-phenyl-isoxazol-4-yl]-benzenesulfonamide::CHEMBL196041

SMILES NS(=O)(=O)c1ccc(cc1)-c1c(CCF)onc1-c1ccccc1

InChI Key InChIKey=FUDHASBGRVLGEV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173290   

TargetProstaglandin G/H synthase 2(Human)
University of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM50173290(4-[5-(2-Fluoro-ethyl)-3-phenyl-isoxazol-4-yl]-benz...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against human recombinant cyclooxygenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM50173290(4-[5-(2-Fluoro-ethyl)-3-phenyl-isoxazol-4-yl]-benz...)
Affinity DataIC50:  2nMAssay Description:Tested for prostaglandin E2 production as a function of COX-2 inhibition using endotoxin-treated murine RAW 264.7 macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed