BDBM50178323 (3S,10R,13S,17S)-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol::CHEMBL77135

SMILES C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@]34C)C1CC[C@@H]2O

InChI Key InChIKey=QADHLRWLCPCEKT-QJIZPQHZSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50178323   

TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178323((3S,10R,13S,17S)-10,13-Dimethyl-2,3,4,7,8,9,10,11,...)
Affinity DataIC50:  210nMAssay Description:Binding affinity to human ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178323((3S,10R,13S,17S)-10,13-Dimethyl-2,3,4,7,8,9,10,11,...)
Affinity DataEC50:  6nMAssay Description:Effect on transactivation of ALP gene expression in HEK293 cells transfected with hERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178323((3S,10R,13S,17S)-10,13-Dimethyl-2,3,4,7,8,9,10,11,...)
Affinity DataIC50:  10nMAssay Description:Binding affinity to human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178323((3S,10R,13S,17S)-10,13-Dimethyl-2,3,4,7,8,9,10,11,...)
Affinity DataEC50:  26nMAssay Description:Effect on transactivation of ALP gene expression in HEK293 cells transfected with hERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178323((3S,10R,13S,17S)-10,13-Dimethyl-2,3,4,7,8,9,10,11,...)
Affinity DataIC50:  212nMAssay Description:Inhibitory activity against ARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed