BDBM50179353 (1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)methanone::CHEMBL382276

SMILES CN1CCN(CC1)C(=O)c1nc2ccccc2[nH]1

InChI Key InChIKey=KCVXUVKSHFDJIV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179353   

TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179353((1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)met...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]histamine from recombinant human histamine H4 receptor in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179353((1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)met...)
Affinity DataKi:  288nMAssay Description:Displacement of [3H]histamine from human H4R expressed in Sf9 cells co-expressing RGS19, Galphai2 and Gbeta1gamma2 after 60 mins by liquid scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed