BDBM50181153 3-(N-hydroxyacetamido)propylphosphonic acid::3-(N-hydroxyformamido)propylphosphonic acid::CHEMBL205338::FR-900098::ammonium 3-(N-hydroxyacetamido)propylphosphonate

SMILES CC(=O)N(O)CCCP(O)(O)=O

InChI Key InChIKey=PKMNDDZSIHLLLI-UHFFFAOYSA-N

Data  1 KI  9 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50181153   

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)
Affinity DataKi:  130nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant DXR expressed in Escherichia coli BL21 (DE3) using DXP as substrate and MgCl2 as cofactor preinc...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)
Affinity DataIC50:  58nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)
Affinity DataIC50:  160nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR assessed as reduction of 1-deoxy-D-xylulose 5-phosphate into 2-C-methyl-D-erythritol-4-phosphate measure...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)
Affinity DataIC50:  160nMAssay Description:Antagonism of phenylephrine stimulated contraction of the rat isolated spleen.More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)
Affinity DataIC50:  28nMAssay Description:Inhibitory concentration against DOXP reductoisomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycolicibacterium smegmatis (strain ATCC 700084 / ...)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)
Affinity DataIC50:  320nMAssay Description:Inhibition of Mycobacterium smegmatis DSM 43756 ATCC 19420 N-terminal his-tagged DXR expressed in XL1-blue Escherichia coli using NADPH and DXP as su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (Trypanosoma cruzi) Trypanothione reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)
Affinity DataIC50:  2.39E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DxrMore data for this Ligand-Target Pair