BDBM50182122 CHEMBL204688::bis(2,4-dinitrophenyl)sulfane

SMILES [O-][N+](=O)c1ccc(Sc2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)c(c1)[N+]([O-])=O

InChI Key InChIKey=DMIUPZAMXYQKBR-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50182122   

TargetThioredoxin reductase(Plasmodium falciparum (isolate 3D7))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50182122(CHEMBL204688 | bis(2,4-dinitrophenyl)sulfane)
Affinity DataKi:  200nMAssay Description:Binding affinity to Plasmodium falciparum TrxR in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase(Plasmodium falciparum (isolate 3D7))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50182122(CHEMBL204688 | bis(2,4-dinitrophenyl)sulfane)
Affinity DataKi:  200nMAssay Description:Binding affinity to Plasmodium falciparum TrxR in presence of thioredoxinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase(Plasmodium falciparum (isolate 3D7))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50182122(CHEMBL204688 | bis(2,4-dinitrophenyl)sulfane)
Affinity DataIC50:  500nMAssay Description:Inhibition of Plasmodium falciparum TrxRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic/2, mitochondrial/3(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50182122(CHEMBL204688 | bis(2,4-dinitrophenyl)sulfane)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human TrxRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed