BDBM50185943 3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE::3-fluoro-N-(1-(4-fluorophenyl)-3-(2-thienyl)-1H-pyrazol-5-yl)benzenesulfonamide::CHEMBL378160

SMILES Fc1ccc(cc1)-n1nc(cc1NS(=O)(=O)c1cccc(F)c1)-c1cccs1

InChI Key InChIKey=GULUFDCOGAXLEP-UHFFFAOYSA-N

Data  2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50185943   

TargetPeroxisome proliferator-activated receptor gamma(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50185943(3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PY...)
Affinity DataEC50:  1.75E+3nMAssay Description:Effect on Gal4/PPAR-gamma-LBD construct transactivation in Huh7 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50185943(3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PY...)
Affinity DataIC50:  512nMAssay Description:Displacement of fluormone PPAR-green from N-terminal His-tagged human PPARgamma-LBD after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50185943(3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PY...)
Affinity DataIC50:  512nMAssay Description:Displacement of [3H]rosiglitazone from PPARgamma by SPAMore data for this Ligand-Target Pair