BDBM50187389 CHEMBL377697::cyclopropanecarboxylic acid {3-[4-(4-cyclohexylmethanesulfonylamino-butyl)-piperazin-1-yl]-phenyl}-amide

SMILES O=C(Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1)C1CC1

InChI Key InChIKey=AKDDQOOXABRYDQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187389   

Target5-hydroxytryptamine receptor 1A(Human)
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50187389(CHEMBL377697 | cyclopropanecarboxylic acid {3-[4-(...)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50187389(CHEMBL377697 | cyclopropanecarboxylic acid {3-[4-(...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of hERG potassium channel in HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed