BDBM50188738 1-isobutyl-1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)-3-m-tolylurea::CHEMBL210070

SMILES CC(C)CN(Cc1ccc(s1)-c1[nH]nc-2c1Cc1cc(CN3CCN(C)CC3)ccc-21)C(=O)Nc1cccc(C)c1

InChI Key InChIKey=CODNFAROPXKNHK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188738   

TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188738(1-isobutyl-1-((5-(6-((4-methylpiperazin-1-yl)methy...)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of FLT1 at 1mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188738(1-isobutyl-1-((5-(6-((4-methylpiperazin-1-yl)methy...)
Affinity DataIC50:  1.72E+4nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188738(1-isobutyl-1-((5-(6-((4-methylpiperazin-1-yl)methy...)
Affinity DataIC50:  164nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed