BDBM50198301 (3aS,10R)-2-butyl-10-(3-hydroxy-phenyl)-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]fluorene-1,3-dione::CHEMBL252340

SMILES CCCCn1c(O)c2Cc3c([nH]c4ccccc34)[C@@H](c3cccc(O)c3)n2c1=O

InChI Key InChIKey=GCCHOAVQJOTOGI-OAQYLSRUSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50198301   

TargetKinesin-like protein KIF11(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50198301((3aS,10R)-2-butyl-10-(3-hydroxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50198301((3aS,10R)-2-butyl-10-(3-hydroxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50198301((3aS,10R)-2-butyl-10-(3-hydroxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of Eg5 ATPase activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKinesin-like protein KIF11(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50198301((3aS,10R)-2-butyl-10-(3-hydroxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50198301((3aS,10R)-2-butyl-10-(3-hydroxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKinesin-like protein KIF11(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50198301((3aS,10R)-2-butyl-10-(3-hydroxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed