BDBM50199365 (E)-(9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl-15-propyl-6,7,8,9,11,12,14,15,17,18-decahydro-5-oxa-8,11,14,17-tetraaza-benzocyclooctadecene-10,13,16-trione::CHEMBL214935

SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC1=O)C(C)C

InChI Key InChIKey=CXNVASKCTNQIAR-WTKIFITDSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50199365   

TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50199365((E)-(9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl...)
Affinity DataKi:  137nMAssay Description:Displacement of [125I]-motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50199365((E)-(9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl...)
Affinity DataKi:  137nMAssay Description:Displacement of [125I]motilin from human MOTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50199365((E)-(9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl...)
Affinity DataIC50:  74nMAssay Description:Antagonist activity against human motilin receptor in aequoscreen cells assessed as inhibition of motilin induced calcium release by aequorin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50199365((E)-(9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl...)
Affinity DataIC50:  74nMAssay Description:Activity at human MOTR expressed in CHO cells assessed as inhibition of motilin-induced calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed