BDBM50209206 (2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodophenyl)methanone::CHEMBL232201::US9725430, Compound 1c::US9962362, Compound 1c

SMILES CCc1oc2ccccc2c1C(=O)c1cc(I)c(O)c(I)c1

InChI Key InChIKey=CZCHIEJNWPNBDE-UHFFFAOYSA-N

Data  2 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50209206   

TargetBaculoviral IAP repeat-containing protein 5(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209206((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodopheny...)
Affinity DataKd:  8.00E+3nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50209206((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodopheny...)
Affinity DataIC50:  3.40E+3nMAssay Description:The compounds were then tested using full-length human recombinant, purified EYA3 and pNPP as a substrate. Compounds were dissolved in DMSO and dilut...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50209206((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodopheny...)
Affinity DataIC50:  3.40E+3nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In DepthDetails US Patent