BDBM50225499 Benoxinate::CHEBI:309594::Oxybuprocaine

SMILES CCCCOc1cc(ccc1N)C(=O)OCCN(CC)CC

InChI Key InChIKey=CMHHMUWAYWTMGS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50225499   

TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225499(Benoxinate | CHEBI:309594 | Oxybuprocaine)
Affinity DataIC50:  3.09E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50225499(Benoxinate | CHEBI:309594 | Oxybuprocaine)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed