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BDBM50240424 3-Ethyl-3-methyl-pyrrolidine-2,5-dione::3-Ethyl-3-methyl-pyrrolidine-2,5-dione (ethosuximide)::3-Ethyl-3-methyl-pyrrolidine-2,5-dione(ethosuximide)::3-ethyl-3-methylpyrrolidine-2,5-dione::CHEMBL696::CI-366::CN-10395::ETHOSUXIMIDE::PM-671::Zarontin::zarontin3-Ethyl-3-methyl-pyrrolidine-2,5-dione

SMILES: CCC1(C)CC(=O)NC1=O

InChI Key: InChIKey=HAPOVYFOVVWLRS-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240424   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Homo sapiens (human))
BDBM50240424
PNG
(3-Ethyl-3-methyl-pyrrolidine-2,5-dione | 3-Ethyl-3...)
Show SMILES CCC1(C)CC(=O)NC1=O
Show InChI InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)
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CHEMBL
DrugBank
KEGG
PC cid
PC sid
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Similars

PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Mayo Foundation

Curated by PDSP Ki Database




Brain Res 304: 1-7 (1984)

More data for this
Ligand-Target Pair
Voltage-gated T-type calcium channel


(Homo sapiens)
BDBM50240424
PNG
(3-Ethyl-3-methyl-pyrrolidine-2,5-dione | 3-Ethyl-3...)
Show SMILES CCC1(C)CC(=O)NC1=O
Show InChI InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>5.00E+6n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of T-type calcium channel alpha1I (unknown origin) by FLIPR


J Med Chem 51: 6471-7 (2008)

More data for this
Ligand-Target Pair