BDBM50247213 3-ethyl-4-(1-(furan-2-ylmethyl)-2,6-dimethylpyridin-4(1H)-ylidene)-2-thioxothiazolidin-5-one::CHEMBL473106::cid_2369069

SMILES [#6]-[#6]-[#7]1-[#6](=S)-[#16]-[#6](=O)\[#6]-1=[#6]-1\[#6]=[#6](-[#6])-[#7](-[#6]-c2ccco2)-[#6](-[#6])=[#6]-1

InChI Key InChIKey=AQWLITYTSYRLNQ-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50247213   

TargetCollagenase 3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50247213(3-ethyl-4-(1-(furan-2-ylmethyl)-2,6-dimethylpyridi...)
Affinity DataIC50:  8.08E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50247213(3-ethyl-4-(1-(furan-2-ylmethyl)-2,6-dimethylpyridi...)
Affinity DataEC50: >1.95E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCollagenase 3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50247213(3-ethyl-4-(1-(furan-2-ylmethyl)-2,6-dimethylpyridi...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of human recombinant MMP13 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50247213(3-ethyl-4-(1-(furan-2-ylmethyl)-2,6-dimethylpyridi...)
Affinity DataEC50:  1.05E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetOxytocin receptor(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50247213(3-ethyl-4-(1-(furan-2-ylmethyl)-2,6-dimethylpyridi...)
Affinity DataEC50:  1.67E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetImportin subunit alpha-1(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50247213(3-ethyl-4-(1-(furan-2-ylmethyl)-2,6-dimethylpyridi...)
Affinity DataEC50:  1.07E+4nMAssay Description:Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay