BDBM50258880 8-(dio-tolylmethyl)-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol::CHEMBL513136

SMILES Cc1ccccc1C(N1C2CCC1CC(O)(C2)c1ccccc1)c1ccccc1C

InChI Key InChIKey=LOSJNRBXNQTUNT-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50258880   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50258880(8-(dio-tolylmethyl)-3-phenyl-8-azabicyclo[3.2.1]oc...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human cloned NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50258880(8-(dio-tolylmethyl)-3-phenyl-8-azabicyclo[3.2.1]oc...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50258880(8-(dio-tolylmethyl)-3-phenyl-8-azabicyclo[3.2.1]oc...)
Affinity DataKi:  131nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50258880(8-(dio-tolylmethyl)-3-phenyl-8-azabicyclo[3.2.1]oc...)
Affinity DataKi:  2.85E+3nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50258880(8-(dio-tolylmethyl)-3-phenyl-8-azabicyclo[3.2.1]oc...)
Affinity DataEC50:  693nMAssay Description:Agonist activity at human mu opioid assessed as stimulation of GDP-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50258880(8-(dio-tolylmethyl)-3-phenyl-8-azabicyclo[3.2.1]oc...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human NOP assessed as stimulation of GDP-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed