BDBM50263365 4-fluoro-N-(2-((4-methoxyphenyl)(phenyl)methylamino)-2-oxoethyl)benzamide::CHEMBL479072

SMILES COc1ccc(cc1)C(NC(=O)CNC(=O)c1ccc(F)cc1)c1ccccc1

InChI Key InChIKey=ZJRBVCCQUXNYDM-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50263365   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50263365(4-fluoro-N-(2-((4-methoxyphenyl)(phenyl)methylamin...)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 transfected in Flp-inTM-CHOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50263365(4-fluoro-N-(2-((4-methoxyphenyl)(phenyl)methylamin...)
Affinity DataEC50:  1.14E+4nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 2 transfected in Flp-inTM-CHOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50263365(4-fluoro-N-(2-((4-methoxyphenyl)(phenyl)methylamin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50263365(4-fluoro-N-(2-((4-methoxyphenyl)(phenyl)methylamin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50263365(4-fluoro-N-(2-((4-methoxyphenyl)(phenyl)methylamin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed