BDBM50272918 CHEMBL456964::N-(2-(1H-Indol-3-yl)ethyl)-3'-fluorobiphenyl-2-carboxamide

SMILES Fc1cccc(c1)-c1ccccc1C(=O)NCCc1c[nH]c2ccccc12

InChI Key InChIKey=VNLGYUNDFJCHRC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272918   

TargetCyclin-dependent kinase 2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50272918(CHEMBL456964 | N-(2-(1H-Indol-3-yl)ethyl)-3'-fluor...)
Affinity DataIC50:  4.17E+5nMAssay Description:Inhibition of human CDK2/GST-cyclin A expressed in Sf9 cells assessed as histone phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 4(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50272918(CHEMBL456964 | N-(2-(1H-Indol-3-yl)ethyl)-3'-fluor...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human CDK4/GST-cyclin D1 expressed in Sf9 cells assessed as retinoblastoma GST-RB152 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed