BDBM50275185 CHEMBL4125687

SMILES CC(C)C[C@H](NC(=O)NCc1cn(Cc2ccccc2OCc2ccccc2)nn1)C(=O)NO

InChI Key InChIKey=XFRYFTSUUZTQBM-NRFANRHFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50275185   

TargetAminopeptidase N(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50275185(CHEMBL4125687)
Affinity DataIC50:  740nMAssay Description:Inhibition of APN in human ES2 cells using L-Leu-pnitroanilide as substrate pretreated for 5 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Pig)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50275185(CHEMBL4125687)
Affinity DataIC50:  89nMAssay Description:Inhibition of APN in porcine kidney microsomes using L-Leu-pnitroanilide as substrate pretreated for 5 mins followed by substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50275185(CHEMBL4125687)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of APN in human PLC/PRF/5 cells using L-Leu-pnitroanilide as substrate pretreated for 5 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed