BDBM50287322 1-{3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-isopropyl-1H-indol-2-yl]-2,2-dimethyl-propyl}-1-hydroxy-urea::CHEMBL39189

SMILES CC(C)c1ccc2n(Cc3ccc(Cl)cc3)c(CC(C)(C)CN(O)C(N)=O)c(SC(C)(C)C)c2c1

InChI Key InChIKey=AIIZMHYSVIPRCK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287322   

LigandPNGBDBM50287322(1-{3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-i...)
Affinity DataIC50:  170nMAssay Description:Inhibition of calcium ionophore (A23187) stimulated LTB4 formation in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50287322(1-{3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-i...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of calcium ionophore (A23187) stimulated LTB4 formation in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50287322(1-{3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-i...)
Affinity DataIC50:  7.50E+3nMAssay Description:Compound was tested for inhibition of 5-lipoxygenase activity in a broken cell supernatant rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article