BDBM50295479 (S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,d]furan-3-sulfonamido)butanoic Acid::CHEMBL550038

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc2c(c1)oc1ccc(cc21)N1CCOC1=O)C(O)=O

InChI Key InChIKey=FWPVXLYOKAOERT-SFHVURJKSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50295479   

LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50:  2.26E+4nMAssay Description:Inhibition of human Aggrecanase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMacrophage metalloelastase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-14(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of human MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human Aggrecanase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeutrophil collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrilysin(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50:  7.83E+3nMAssay Description:Inhibition of human MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50:  66nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50:  5.46E+3nMAssay Description:Inhibition of human MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMacrophage metalloelastase(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50:  72nMAssay Description:Inhibition of rat MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMacrophage metalloelastase(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50:  27nMAssay Description:Inhibition of mouse MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMacrophage metalloelastase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50:  106nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50:  318nMAssay Description:Inhibition of human MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed