BDBM50296645 CHEMBL559401::N-cyclopropyl-3-(1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-ylamino)-4-methylbenzamide::N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide

SMILES Cc1ccc(cc1Nc1cc(=O)n(C)c2n(ncc12)-c1ccc(F)cc1F)C(=O)NC1CC1

InChI Key InChIKey=WMEYCLAVMZKZCS-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296645   

TargetMitogen-activated protein kinase 14(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50296645(CHEMBL559401 | N-cyclopropyl-3-(1-(2,4-difluorophe...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50296645(CHEMBL559401 | N-cyclopropyl-3-(1-(2,4-difluorophe...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human recombinant p38alpha assessed as phosphorylation of ATF2 by scintillation proximity assayMore data for this Ligand-Target Pair