BDBM50000780 2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide::2-(3,4-dichlorophenyl)-N-methyl-N-[(2S)-2-(pyrrolidin-1-yl)cyclohexyl]acetamide::CHEMBL593781
SMILES CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1
InChI Key InChIKey=VQLPLYSROCPWFF-ROUUACIJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50000780
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]diprenorphine from human recombinant mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.890nMAssay Description:Compound was evaluated for binding affinity towards kappa opioid receptor using [3H](-)-U-69,593 in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membrane measured after 30 mins by liquid scintillation counting m...More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [3H]-diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bin...More data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:In vitro inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Digestive
Curated by ChEMBL
National Institute of Digestive
Curated by ChEMBL
Affinity DataKi: 594nMAssay Description:Compound was evaluated for binding affinity towards sigma opioid receptor using [3H](+)-3-PPP in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in CHO cell membrane measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DPDPE from rat delta opioid receptor expressed in CHO cell membrane measured after 30 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataEC50: 46nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane incubated for 1 hr by [35S]GTPgammaS binding based liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Agonist activity at mouse kappa opioid receptor-1 expressed in CHO cell membranes assessed as [35S]GTPgammaS binding incubated for 60 mins by scintil...More data for this Ligand-Target Pair
Affinity DataEC50: 46nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:Activity at kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 36nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair