BDBM50304393 (R)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propylamine::CHEMBL594585

SMILES NCC[C@@H](Oc1cccc2ccccc12)c1cccs1

InChI Key InChIKey=ZMXLKLOJDLMZFC-MRXNPFEDSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50304393   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304393((R)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [125I]RTI-55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304393((R)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataKi:  953nMAssay Description:Displacement of [125I]RTI-55 from human recombinant NET expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304393((R)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataKi:  3.55E+3nMAssay Description:Displacement of [125I]RTI-55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304393((R)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataIC50:  188nMAssay Description:Inhibition of [3H]NE reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304393((R)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]DA reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304393((R)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of [3H]5HT reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed