BDBM50311887 6-bromo-N-(3-chlorophenyl)quinazolin-4-amine::CHEMBL1079374::cid_720635

SMILES Clc1cccc(Nc2ncnc3ccc(Br)cc23)c1

InChI Key InChIKey=LYKXFKUSOXETGV-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50311887   

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50311887(6-bromo-N-(3-chlorophenyl)quinazolin-4-amine | CHE...)
Affinity DataKi:  116nMAssay Description:Displacement of [3H]3methoxy-5-(pyridin-2-ylethynyl)pyridine from rat mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50311887(6-bromo-N-(3-chlorophenyl)quinazolin-4-amine | CHE...)
Affinity DataIC50:  256nMAssay Description:Antagonist activity at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMajor prion protein(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50311887(6-bromo-N-(3-chlorophenyl)quinazolin-4-amine | CHE...)
Affinity DataIC50:  6.28E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMetabotropic glutamate receptor 1(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50311887(6-bromo-N-(3-chlorophenyl)quinazolin-4-amine | CHE...)
Affinity DataIC50:  398nMAssay Description:Antagonist activity at rat mGluR1 expressed in BHK cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed