BDBM50322579 2-(trifluoromethyl)-9H-carbazole::CHEMBL1173704

SMILES FC(F)(F)c1ccc2c(c1)[nH]c1ccccc21

InChI Key InChIKey=HWUDQSLQFQHKSV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50322579   

TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50322579(2-(trifluoromethyl)-9H-carbazole | CHEMBL1173704)
Affinity DataIC50:  210nMAssay Description:Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) expressed in bacteria incubated for 30 mins prior to ATP addition measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50322579(2-(trifluoromethyl)-9H-carbazole | CHEMBL1173704)
Affinity DataIC50:  210nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50322579(2-(trifluoromethyl)-9H-carbazole | CHEMBL1173704)
Affinity DataIC50:  260nMAssay Description:Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed