BDBM50323040 1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylaminocarbonyl)oxime::CHEMBL1210154

SMILES CC(=NOC(=O)Nc1ccccc1)c1cccc(c1)-c1cccs1

InChI Key InChIKey=CQUWKHKELQQYRI-UHFFFAOYSA-N

Data  46 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 46 hits for monomerid = 50323040   

TargetBeta-2 adrenergic receptor(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H](-)CGP 12177 from human recombinant beta2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse TRPV1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]Ketanserin from human recombinant 5HT2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rat)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]CYP from 5HT1B receptor expressed in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]SQ 29548 from human recombinant TXA2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]nociceptin from human recombinant ORL1 receptor expressed in H recombinant HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rat)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]U69593 from rat recombinant kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]Tyr3-neurotensin from human recombinant NT1 receptor expressed in H recombinant CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]peptide YY from human recombinant Y2 receptor expressed in KAN-TS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]peptide YY from human recombinant Y1 receptor expressed in SK-NM- cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]SR 142801 from human recombinant NK3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]NKA from human recombinant NK2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]4-DAMP from human recombinant muscarinic M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]AF-DX 384 from human recombinant muscarinic M2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]pirenzepine from human recombinant muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]NDP-a-MSH from human recombinant MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]APT from human recombinant histamine H2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]MIP-1a from human recombinant CCR1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]IL-8 from human recombinant CXCR2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGalanin receptor type 2(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]Galanin from human recombinant GAL2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]endothelin-1 from human recombinant ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from human recombinant dopamine D2S receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]SCH 23390 from human recombinant dopamine D1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]CCK-8 from human recombinant CCKA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]bradykinin from human recombinant bradykinin B2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I][Sar1,Ile8]-AT II from human recombinant AT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H](-)CGP 12177 from human recombinant beta-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]AB-MECA from human recombinant A3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]CGS21680 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DPCPX from human recombinant A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidylserine lipase ABHD12(Mouse)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse brain MAGLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Mouse)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of mouse brain CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mouse)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mouse)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50:  8nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]imipramine from human recombinant 5HT transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]BTCP from human recombinant dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]apamin from SK+Ca channel in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]AVP from human recombinant V1a receptor expressed in H recombinant CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT5A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
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Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]BRL 43694 from human recombinant 5HT3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed