BDBM50323733 1-(1-METHYLETHYL)-3-(PYRIDIN-3-YLETHYNYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE::1-isopropyl-3-(pyridin-3-ylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL1213119
SMILES CC(C)n1nc(C#Cc2cccnc2)c2c(N)ncnc12
InChI Key InChIKey=NYVMTNNWZOHTJT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50323733
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Medical Research Council-Laboratory of Molecular Biology
Curated by ChEMBL
Medical Research Council-Laboratory of Molecular Biology
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of p110alphaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Medical Research Council-Laboratory of Molecular Biology
Curated by ChEMBL
Medical Research Council-Laboratory of Molecular Biology
Curated by ChEMBL
Affinity DataIC50: 664nMAssay Description:Inhibition of p110betaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of p110deltaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Medical Research Council-Laboratory of Molecular Biology
Curated by ChEMBL
Medical Research Council-Laboratory of Molecular Biology
Curated by ChEMBL
Affinity DataIC50: 113nMAssay Description:Inhibition of p110gammaMore data for this Ligand-Target Pair