BDBM50328381 CHEMBL1258147::ethyl 2-morpholino-4-phenyl-7-propyl-6-(3-propyl-1,2,4-oxadiazol-5-yl)pyrrolo[1,2-b]pyridazine-5-carboxylate

SMILES CCCc1noc(n1)-c1c(CCC)n2nc(cc(-c3ccccc3)c2c1C(=O)OCC)N1CCOCC1

InChI Key InChIKey=IKTGWCGZNVABQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328381   

TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328381(CHEMBL1258147 | ethyl 2-morpholino-4-phenyl-7-prop...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328381(CHEMBL1258147 | ethyl 2-morpholino-4-phenyl-7-prop...)
Affinity DataIC50:  65nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed