BDBM50333014 8-methyl-4-phenyl-1H-benzo[b][1,4]diazepin-2(3H)-one::CHEMBL394287

SMILES Cc1ccc2N=C(CC(=O)Nc2c1)c1ccccc1

InChI Key InChIKey=SCWDIXHHIUWDED-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333014   

TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50333014(8-methyl-4-phenyl-1H-benzo[b][1,4]diazepin-2(3H)-o...)
Affinity DataIC50:  6.40E+6nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50333014(8-methyl-4-phenyl-1H-benzo[b][1,4]diazepin-2(3H)-o...)
Affinity DataIC50:  6.40E+3nMAssay Description:Displacement of [3H]LY354740 from rat mGluR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50333014(8-methyl-4-phenyl-1H-benzo[b][1,4]diazepin-2(3H)-o...)
Affinity DataIC50:  6.40E+3nMAssay Description:Displacement of [3H]LY354740 from rat mGluR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50333014(8-methyl-4-phenyl-1H-benzo[b][1,4]diazepin-2(3H)-o...)
Affinity DataIC50:  6.40E+3nMAssay Description:Displacement of [3H]LY354740 from recombinant rat mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed