BDBM50341675 (E)-3-(4-chlorobenzylidene)chroman-4-one::3-(4-Chlorobenzylidene)-2,3-dihydro-1-benzopyran-4-one::CHEMBL452004

SMILES Clc1ccc(\C=C2/COc3ccccc3C2=O)cc1

InChI Key InChIKey=DCQYQJQFGBXYDD-FMIVXFBMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50341675   

TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50341675((E)-3-(4-chlorobenzylidene)chroman-4-one | 3-(4-Ch...)
Affinity DataIC50:  154nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50341675((E)-3-(4-chlorobenzylidene)chroman-4-one | 3-(4-Ch...)
Affinity DataIC50:  156nMAssay Description:Inhibition of human MAO-B using kynuramine as substrate incubated for 20 mins by fluorescence spectrophotometry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50341675((E)-3-(4-chlorobenzylidene)chroman-4-one | 3-(4-Ch...)
Affinity DataIC50:  1.55E+5nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed