BDBM50345230 1-benzofuran-2-carboxylic acid::CHEMBL84095::benzofuran-2-carboxylic acid

SMILES OC(=O)c1cc2ccccc2o1

InChI Key InChIKey=OFFSPAZVIVZPHU-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 Kd

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50345230   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50345230(1-benzofuran-2-carboxylic acid | CHEMBL84095 | ben...)
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of FITC-AHx-KALETLRRVGDGVQRNHETAF-NH2 from human MCl1 (172 to 327) expressed in Escherichia coli BL21 (DE3) after 1 hr by fluorescence p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPantothenate synthetase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50345230(1-benzofuran-2-carboxylic acid | CHEMBL84095 | ben...)
Affinity DataKd:  1.00E+6nMAssay Description:Binding affinity to Mycobacterium tuberculosis Pantothenate synthetaseMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50345230(1-benzofuran-2-carboxylic acid | CHEMBL84095 | ben...)
Affinity DataIC50:  1.19E+5nMAssay Description:Inhibition of human Pim1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 45 mins by off-chip mobility shift methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed